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2025, Vol: 2, Issue: 2
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Original Article
Online Published: 28 May 2025
 


Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does

Maryam Bashir Darma, Kabir Ibrahim, Bello Sabo, Aliyu Abubakar Yahaya, Hassan Abubakar.


Abstract
Aim: This study evaluated the effects of the methanolic leaf extract of Newbouldia laevis on the reproductive performance of rabbit does.
Methods: Twenty rabbit does, aged 6 ± 2 months and weighing an average of 1.40 ± 2.00 kg, were housed individually and randomly assigned to four groups of five each. Groups A, B, and C received the leaf extract at doses of 1000 mg/kg, 500 mg/kg, and 250 mg/kg, respectively, while group D served as the control and was given only a standard rabbit diet and water ad libitum for 48 days. The does were bred on day 27 of extract administration and monitored for mortality, conception, and kindling rates.
Results: Phytochemical analysis of the extract revealed the presence of flavonoids, tannins, terpenes, saponins, alkaloids, phenols, and cardiac glycosides, with an LD50 of ≥ 1000 mg/kg. Mortality rates observed were 60.0%, 20%, and 0% in groups A, B, C, and D, respectively. Conception rates in groups A and C were 100.0%, and in groups B and D were 75.0%. The kindling rate in all the groups was 100.0%.
Conclusion: Conception rates were not affected in rabbit does fed 1000 mg/kg and 250 mg/kg of the leaf extract, while at 500 mg/kg, they were affected slightly. Similarly, the kindling rate was not affected in all the groups. Research to explore the effects of the leaf extract from 0 to 250 mg/kg to identify a safer therapeutic dose. Other reproductive parameters in both male and female rabbits are recommended.

Key words: Methanolic Leaf Extract, Newbouldia laevis, Rabbit Does, Reproductive performance.


 
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How to Cite this Article
Pubmed Style

Darma MB, Ibrahim K, Sabo B, Yahaya AA, Abubakar H. Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. J Exp Lab Med. 2025; 2(2): 84-89. doi:10.5455/JELM.20250423010955

Web Style

Darma MB, Ibrahim K, Sabo B, Yahaya AA, Abubakar H. Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. https://www.wisdomgale.com/jelm/?mno=302657914 [Access: May 30, 2025]. doi:10.5455/JELM.20250423010955

AMA (American Medical Association) Style

Darma MB, Ibrahim K, Sabo B, Yahaya AA, Abubakar H. Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. J Exp Lab Med. 2025; 2(2): 84-89. doi:10.5455/JELM.20250423010955


Vancouver/ICMJE Style

Darma MB, Ibrahim K, Sabo B, Yahaya AA, Abubakar H. Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. J Exp Lab Med. (2025), [cited May 30, 2025]; 2(2): 84-89. doi:10.5455/JELM.20250423010955


Harvard Style

Darma, M. B., Ibrahim, . K., Sabo, . B., Yahaya, . A. A. & Abubakar, . H. (2025) Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. J Exp Lab Med, 2 (2), 84-89. doi:10.5455/JELM.20250423010955


Turabian Style

Darma, Maryam Bashir, Kabir Ibrahim, Bello Sabo, Aliyu Abubakar Yahaya, and Hassan Abubakar. 2025. Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. Journal of Experimental and Laboratory Medicine, 2 (2), 84-89. doi:10.5455/JELM.20250423010955


Chicago Style

Darma, Maryam Bashir, Kabir Ibrahim, Bello Sabo, Aliyu Abubakar Yahaya, and Hassan Abubakar. "Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does." Journal of Experimental and Laboratory Medicine 2 (2025), 84-89. doi:10.5455/JELM.20250423010955


MLA (The Modern Language Association) Style

Darma, Maryam Bashir, Kabir Ibrahim, Bello Sabo, Aliyu Abubakar Yahaya, and Hassan Abubakar. "Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does." Journal of Experimental and Laboratory Medicine 2.2 (2025), 84-89. Print. doi:10.5455/JELM.20250423010955


APA (American Psychological Association) Style

Darma, M. B., Ibrahim, . K., Sabo, . B., Yahaya, . A. A. & Abubakar, . H. (2025) Effects of the Methanolic Leaf Extract of Newbouldia Laevis on Reproductive Performance In Rabbit Does. Journal of Experimental and Laboratory Medicine, 2 (2), 84-89. doi:10.5455/JELM.20250423010955


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