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2024, Vol: 1, Issue: 2
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Case Report
Online Published: 10 Oct 2024
 


Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease

Gurdeep Singh, William Cobb, Haven Ward, Arooj Mian, Tien-Anh Tran, Karen Echeverria-Beltran, Mustafa Arain, Armando Rosales.


Abstract
Introduction: Rosai-Dorfman disease (RDD) is a benign, proliferative disease of non-Langerhans cell histiocytes typically involving lymphoid tissue. Pancreatic involvement is extremely rare.

Case Description: Our case is of a 53-year-old female who originally presented with vague epigastric abdominal pain. Magnetic resonance imaging (MRI) revealed a mass in the pancreatic body suspicious for malignancy. The patient successfully underwent a robotic-assisted subtotal pancreatectomy and splenectomy. The final pathology revealed sheets of foamy histiocytes with enlarged vesicular nuclei and nucleoli. Immunohistochemical testing was positive for S-100 protein and CD163 and negative for CD1a and ALK-1, establishing a diagnosis of pancreatic Rosai-Dorfman disease. Next generation sequencing was positive for an F53L variant mutation of the MAP2K1 gene.

Discussion: Overall, there is no uniform approach for RDD treatment, treatment is usually tailored to the individual’s clinical picture. Here we describe a novel technique of robotic-assisted resection of pancreatic Rosai-Dorfman disease.

Key words: Rosai-Dorfman Disease; pancreas; robotic subtotal pancreatectomy; histiocytes


 
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How to Cite this Article
Pubmed Style

Singh G, Cobb W, Ward H, Mian A, Tran T, Echeverria-Beltran K, Arain M, Rosales A, . Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Rep Ser Med. Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638

Web Style

Singh G, Cobb W, Ward H, Mian A, Tran T, Echeverria-Beltran K, Arain M, Rosales A, . Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. https://www.wisdomgale.com/crsm/?mno=219822 [Access: October 22, 2024]. doi:10.5455/CRSM.20240910083638

AMA (American Medical Association) Style

Singh G, Cobb W, Ward H, Mian A, Tran T, Echeverria-Beltran K, Arain M, Rosales A, . Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Rep Ser Med. Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


Vancouver/ICMJE Style

Singh G, Cobb W, Ward H, Mian A, Tran T, Echeverria-Beltran K, Arain M, Rosales A, . Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Rep Ser Med, [cited October 22, 2024]; Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


Harvard Style

Singh, G., Cobb, W., Ward, H., Mian, A., Tran, T., Echeverria-Beltran, K., Arain, M., Rosales, A. & (2024) Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Rep Ser Med, Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


Turabian Style

Singh, Gurdeep, William Cobb, Haven Ward, Arooj Mian, Tien-Anh Tran, Karen Echeverria-Beltran, Mustafa Arain, Armando Rosales, and . 2024. Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Reports and Series in Medicine, Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


Chicago Style

Singh, Gurdeep, William Cobb, Haven Ward, Arooj Mian, Tien-Anh Tran, Karen Echeverria-Beltran, Mustafa Arain, Armando Rosales, and . "Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease." Case Reports and Series in Medicine Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


MLA (The Modern Language Association) Style

Singh, Gurdeep, William Cobb, Haven Ward, Arooj Mian, Tien-Anh Tran, Karen Echeverria-Beltran, Mustafa Arain, Armando Rosales, and . "Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease." Case Reports and Series in Medicine Online First: 10 Oct, 2024. Web. 22 Oct 2024 doi:10.5455/CRSM.20240910083638


APA (American Psychological Association) Style

Singh, G., Cobb, W., Ward, H., Mian, A., Tran, T., Echeverria-Beltran, K., Arain, M., Rosales, A. & (2024) Robotic-Assisted Resection of Pancreatic Rosai-Dorfman Disease. Case Reports and Series in Medicine, Online First: 10 Oct, 2024. doi:10.5455/CRSM.20240910083638


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