Abstract
This scientific article highlights ten uncommon endocrine and metabolic disorders, including Whipple's disease, Pediatric Acute-onset Neuropsychiatric Syndrome (PANDAS)/Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANS), Mevalonic Aciduria Spectrum Disorders (MASDs), McCune-Albright Syndrome (MAS), Carney Triad, Fabkin Deficiency, Nesfatin-1-like Peptide (NLP), Bile Acid Malabsorption (BAM), Immune Checkpoint Inhibitors (ICIs) and Congenital Hepatic Fibrosis (CHF). These conditions present diverse symptoms, from gastrointestinal issues to neurological problems and endocrine dysfunction. While research has advanced our understanding of these disorders, many aspects remain enigmatic. Studying these rare conditions offers potential insights into common health problems and could lead to improved diagnosis, treatment and potentially even cures. Further research is essential to unravel the complexities of these disorders and develop targeted interventions.

Key words: Bile Acid Malabsorption (BAM), Carney Triad, Congenital Hepatic Fibrosis (CHF), Fabkin Deficiency, Immune Checkpoint Inhibitors (ICIs), McCune-Albright Syndrome (MAS), Mevalonic Aciduria Spectrum Disorders (MASDs), Nesfatin-1-like Peptide (NLP), PANDAS/PANS, Whipple's Disease