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2025, Vol: 2, Issue: 1
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Original Article
Online Published: 31 Dec 2024
 


Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq

Asmaa Abdelaziz Mohamed.


Abstract
This investigation aimed to evaluate the quality of specific lisinopril products available in pharmacies in Iraq. Various measures can ensure their quality and efficacy, such as utilizing quality control metrics, specifically the variability of weight, friability, content, disintegration time, and release. Depending on the results, the disintegration time for Lisinopril 20 mg tablets, Accord; Lisinopril 20 mg tablets; Bristol Lisinopril 20 mg tablets, India was 1.1, 2.5 and 0.75 minutes, respectively. All products had released ≥ 80% of their content after 30 minutes, and the content homogeneity was within the limit. The disintegration rate of Lisnop 20 mg tablets was the quickest, whereas that of Lisinopril 20 mg, Accord was the slowest. Moreover, Lisinopril 20 mg tablets, Accord tablets revealed the quickest disintegration and release 93% after 30 min and may exhibit the quickest response after administration. The results indicated that all products met the specified requirements of the United States and British Pharmacopeia. However, the best brand was Lisinopril 20 mg tablets, Accord which had the fastest release (93% after 30 minutes) and the least disintegration time.

Key words: lisinopril, assessment, hardness, dissolution, disintegration.


 
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Pubmed Style

Asmaa abdelaziz mohamed|. Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. J Pharmacol Pharm Res. 2025; 2(1): 1-5. doi:10.5455/JPPR.20241208052206

Web Style

Asmaa abdelaziz mohamed|. Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. https://www.wisdomgale.com/jppr/?mno=302657766 [Access: January 08, 2025]. doi:10.5455/JPPR.20241208052206

AMA (American Medical Association) Style

Asmaa abdelaziz mohamed|. Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. J Pharmacol Pharm Res. 2025; 2(1): 1-5. doi:10.5455/JPPR.20241208052206


Vancouver/ICMJE Style

Asmaa abdelaziz mohamed|. Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. J Pharmacol Pharm Res. (2025), [cited January 08, 2025]; 2(1): 1-5. doi:10.5455/JPPR.20241208052206


Harvard Style

Asmaa abdelaziz mohamed| (2025) Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. J Pharmacol Pharm Res, 2 (1), 1-5. doi:10.5455/JPPR.20241208052206


Turabian Style

Asmaa abdelaziz mohamed|. 2025. Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. Journal of Pharmacological and Pharmaceutical Research, 2 (1), 1-5. doi:10.5455/JPPR.20241208052206


Chicago Style

Asmaa abdelaziz mohamed|. "Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq." Journal of Pharmacological and Pharmaceutical Research 2 (2025), 1-5. doi:10.5455/JPPR.20241208052206


MLA (The Modern Language Association) Style

Asmaa abdelaziz mohamed|. "Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq." Journal of Pharmacological and Pharmaceutical Research 2.1 (2025), 1-5. Print. doi:10.5455/JPPR.20241208052206


APA (American Psychological Association) Style

Asmaa abdelaziz mohamed| (2025) Comparative In-vitro assessment of some pharmaceutical brands of lisinopril tablets marketed in Iraq. Journal of Pharmacological and Pharmaceutical Research, 2 (1), 1-5. doi:10.5455/JPPR.20241208052206


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