E-ISSN 2983-7561
 

Original Article
Online Published: 18 Sep 2024
 


Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients

umar Musa Usman, YAKUBU IBRAHIM ANAS, Bakare Tomori Abdulfatai, Sani Bako Abubakar, Abubakar Ahmad, Bello Amira, Abdullahi Uzairu, zakariyya Abdurrahman, Abdulaziz Danmadami Mohammad, Sanusi Yusuf Abdallah, Aliyu Ladan, Habibu Bunza Abubakar, Umar Babangida Bashir, Junaidu Sarki, Abdulaziz Hadi Ibrahim.


Abstract
BACKGROUND: Sickle cell disease (SCD) is highly prevalent in Africa, especially in Nigeria, the most populous country, and is associated with a high mortality rate. Depression, common among individuals with SCD, correlates with increased pain intensity and opioid misuse, leading to poorer outcomes and diminished quality of life in these patients.
AIM: To determine whether major depressive disorder is a predictor of opioid use disorder among patients with sickle cell disease.
MATERIALS AND METHODS: This cross-sectional study was conducted at UDUTH Sokoto and employed psychometric instruments to evaluate patients with SCD. A systematic sampling technique was utilized, and data analyzed using SPSS version 25. Chi-square tests and regression analysis were employed to assess associations and identify predictors, respectively.
RESULTS: The study found statistically significant associations between opioid use disorder (OUD) and the lack of insurance services (p-value = 0.008), major depressive disorder (p-value < 0.001), and elevated pain scores (p-value = 0.003), but not with hemoglobin type (p-value = 0.229). OUD was also more prevalent among respondents with moderate to severe depression (p-value = 0.017). However, only major depressive disorder was identified as a predictor of OUD (AOR: 0.174, 95% CI: 0.067–0.452, p-value < 0.001).
CONCLUSION: The study identified major depressive disorder as a predictor of OUD among patients with SCD, this underscores the necessity for routine depression screening and timely intervention in this population.
Keywords: Major depressive disorder, Opioid use disorder, Sickle cell disease.

Key words: Major depressive disorder, Opioid use disorder, Sickle cell disease.


 
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How to Cite this Article
Pubmed Style

Usman uM, ANAS YI, Abdulfatai BT, Abubakar SB, Ahmad A, Amira B, Uzairu A, Abdurrahman z, ADM, Abdallah SY, Ladan A, Abubakar HB, Bashir UB, Sarki J, Ibrahim AH. Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. J Med Res Rev. 2024; 3(1): 23-31. doi:10.5455/JMRR.20240901020050


Web Style

Usman uM, ANAS YI, Abdulfatai BT, Abubakar SB, Ahmad A, Amira B, Uzairu A, Abdurrahman z, ADM, Abdallah SY, Ladan A, Abubakar HB, Bashir UB, Sarki J, Ibrahim AH. Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. https://www.wisdomgale.com/jmrr/?mno=218201 [Access: October 12, 2024]. doi:10.5455/JMRR.20240901020050


AMA (American Medical Association) Style

Usman uM, ANAS YI, Abdulfatai BT, Abubakar SB, Ahmad A, Amira B, Uzairu A, Abdurrahman z, ADM, Abdallah SY, Ladan A, Abubakar HB, Bashir UB, Sarki J, Ibrahim AH. Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. J Med Res Rev. 2024; 3(1): 23-31. doi:10.5455/JMRR.20240901020050



Vancouver/ICMJE Style

Usman uM, ANAS YI, Abdulfatai BT, Abubakar SB, Ahmad A, Amira B, Uzairu A, Abdurrahman z, ADM, Abdallah SY, Ladan A, Abubakar HB, Bashir UB, Sarki J, Ibrahim AH. Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. J Med Res Rev. (2024), [cited October 12, 2024]; 3(1): 23-31. doi:10.5455/JMRR.20240901020050



Harvard Style

Usman, u. M., ANAS, . Y. I., Abdulfatai, . B. T., Abubakar, . S. B., Ahmad, . A., Amira, . B., Uzairu, . A., Abdurrahman, . z., , . A. D. M., Abdallah, . S. Y., Ladan, . A., Abubakar, . H. B., Bashir, . U. B., Sarki, . J. & Ibrahim, . A. H. (2024) Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. J Med Res Rev, 3 (1), 23-31. doi:10.5455/JMRR.20240901020050



Turabian Style

Usman, umar Musa, YAKUBU IBRAHIM ANAS, Bakare Tomori Abdulfatai, Sani Bako Abubakar, Abubakar Ahmad, Bello Amira, Abdullahi Uzairu, zakariyya Abdurrahman, Abdulaziz Danmadami Mohammad, Sanusi Yusuf Abdallah, Aliyu Ladan, Habibu Bunza Abubakar, Umar Babangida Bashir, Junaidu Sarki, and Abdulaziz Hadi Ibrahim. 2024. Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. Journal of Medical Research and Reviews, 3 (1), 23-31. doi:10.5455/JMRR.20240901020050



Chicago Style

Usman, umar Musa, YAKUBU IBRAHIM ANAS, Bakare Tomori Abdulfatai, Sani Bako Abubakar, Abubakar Ahmad, Bello Amira, Abdullahi Uzairu, zakariyya Abdurrahman, Abdulaziz Danmadami Mohammad, Sanusi Yusuf Abdallah, Aliyu Ladan, Habibu Bunza Abubakar, Umar Babangida Bashir, Junaidu Sarki, and Abdulaziz Hadi Ibrahim. "Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients." Journal of Medical Research and Reviews 3 (2024), 23-31. doi:10.5455/JMRR.20240901020050



MLA (The Modern Language Association) Style

Usman, umar Musa, YAKUBU IBRAHIM ANAS, Bakare Tomori Abdulfatai, Sani Bako Abubakar, Abubakar Ahmad, Bello Amira, Abdullahi Uzairu, zakariyya Abdurrahman, Abdulaziz Danmadami Mohammad, Sanusi Yusuf Abdallah, Aliyu Ladan, Habibu Bunza Abubakar, Umar Babangida Bashir, Junaidu Sarki, and Abdulaziz Hadi Ibrahim. "Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients." Journal of Medical Research and Reviews 3.1 (2024), 23-31. Print. doi:10.5455/JMRR.20240901020050



APA (American Psychological Association) Style

Usman, u. M., ANAS, . Y. I., Abdulfatai, . B. T., Abubakar, . S. B., Ahmad, . A., Amira, . B., Uzairu, . A., Abdurrahman, . z., , . A. D. M., Abdallah, . S. Y., Ladan, . A., Abubakar, . H. B., Bashir, . U. B., Sarki, . J. & Ibrahim, . A. H. (2024) Depression as a Predictor of Opioid Use Disorder in Sickle Cell Disease Patients. Journal of Medical Research and Reviews, 3 (1), 23-31. doi:10.5455/JMRR.20240901020050