E-ISSN 2983-7561
 

Research Article
Online Published: 29 Jul 2024
 


Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention

Deniz Elcik, Mikail Yarlioglu, Fatih Oksuz, Mustafa Duran, Mehmet Tugrul Inanc.


Abstract
Aim: This study aimed to evaluate lymphocyte to monocyte ratio (LMR) for risk of CIN in patients with ACS undergoing PCI.
Methods: A total of 1001 ACS patients between 2017 and 2021 were included in the study. CIN was defined as an increase in serum creatinine level of ≥0.5 mg/dL or ≥ 25% above baseline within 72 hours after the procedure. Patients were divided into two groups: patients with and without CIN. Demographics, clinical risk factors, angiographic and laboratory parameters, CIN incidence, and other in hospital clinical outcomes were compared between two groups.
Results: LMR at baseline was significantly lower in patients who developed CIN compared to those who did not (2.1±0.9 and 3.9±1.7, respectively; P < 0.001). In receiver operating characteristic analysis showed that at a cutoff of ≤3, the value of LMR exhibited 80.17 % sensitivity and 70.96% specificity for detecting CIN. At multivariate analyses, LMR ≤3 value (OR 5.525, 95% CI 2.518-12.123; P < 0.001) was one of significant independent predictors of CIN.
Conclusion: Our study suggested that LMR level on admission was independently associated with the development of CIN after PCI in patients with ACS.

Key words: ACS, CIN, lymphocyte to monocyte ratio


 
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How to Cite this Article
Pubmed Style

Elcik D, Yarlioglu M, Oksuz F, Duran M, Inanc MT, . Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. J Med Res Rev. 2024; 2(4): 110-119. doi:10.5455/JMRR.20240621072959


Web Style

Elcik D, Yarlioglu M, Oksuz F, Duran M, Inanc MT, . Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. https://www.wisdomgale.com/jmrr/?mno=206558 [Access: October 19, 2024]. doi:10.5455/JMRR.20240621072959


AMA (American Medical Association) Style

Elcik D, Yarlioglu M, Oksuz F, Duran M, Inanc MT, . Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. J Med Res Rev. 2024; 2(4): 110-119. doi:10.5455/JMRR.20240621072959



Vancouver/ICMJE Style

Elcik D, Yarlioglu M, Oksuz F, Duran M, Inanc MT, . Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. J Med Res Rev. (2024), [cited October 19, 2024]; 2(4): 110-119. doi:10.5455/JMRR.20240621072959



Harvard Style

Elcik, D., Yarlioglu, M., Oksuz, F., Duran, M., Inanc, M. T. & (2024) Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. J Med Res Rev, 2 (4), 110-119. doi:10.5455/JMRR.20240621072959



Turabian Style

Elcik, Deniz, Mikail Yarlioglu, Fatih Oksuz, Mustafa Duran, Mehmet Tugrul Inanc, and . 2024. Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. Journal of Medical Research and Reviews, 2 (4), 110-119. doi:10.5455/JMRR.20240621072959



Chicago Style

Elcik, Deniz, Mikail Yarlioglu, Fatih Oksuz, Mustafa Duran, Mehmet Tugrul Inanc, and . "Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention." Journal of Medical Research and Reviews 2 (2024), 110-119. doi:10.5455/JMRR.20240621072959



MLA (The Modern Language Association) Style

Elcik, Deniz, Mikail Yarlioglu, Fatih Oksuz, Mustafa Duran, Mehmet Tugrul Inanc, and . "Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention." Journal of Medical Research and Reviews 2.4 (2024), 110-119. Print. doi:10.5455/JMRR.20240621072959



APA (American Psychological Association) Style

Elcik, D., Yarlioglu, M., Oksuz, F., Duran, M., Inanc, M. T. & (2024) Relationship between Lymphocyte to Monocyte Ratio and Contrast-Induced Nephropathy in Acute Coronary Syndrome patients treated with Percutaneous Coronary Intervention. Journal of Medical Research and Reviews, 2 (4), 110-119. doi:10.5455/JMRR.20240621072959